or a .45 caliber sized hole in the opponents forehead...
Often.....though don't count on a bullet in the head to stop the fight.....especially from a lessor caliber.
Anecdotal true story:
I know a gentleman who's spent his life skirting the law.....we'll call him 'Dave'. He and another gentleman who used to be 'business' partners had a falling out.....we'll call the other man 'Ken'. Both of these men are the kind of rough men prone to violence that most folks really never meet.
At any rate some threats had been made back and forth and Dave, knowing Ken's unpredictable violent nature and mental instability took them very seriously. One day while Dave was at a mutual friends house, Ken shows up there. As an example of how violence in the REALLY REAL world begins, Ken walks in and sees Dave sitting at a kitchen table and walks over and in a pleasant manner says 'Hi'.
Dave, having decent instincts, already has his 9mm Ruger in his hand next to his right leg out of sight responds. 'Hi Ken'......and without missing a beat Ken raises a .22 caliber revolver and fires a shot point blank at Dave, striking him in the forehead. Dave falls backwards in his chair as Ken fires another shot, which passes through the edge of his left bicep.
Now, Dave doesn't know he's been shot in the forehead, but he does know he's being shot at. Dave rolls backwards and lifts his 9mm and he and Ken exchange multiple shots as Dave is running down the hallway.
Dave, being a decent shot, has managed to strike Ken 9 times, most of them in the upper torso, and put 9mm rounds in to Ken's liver and lungs and a couple of other organs. Dave reloads and Ken is laying on the floor. Dave walks back in with his now reloaded 9mm and Ken starts begging him to call an ambulance. Dave tells him he's not calling anything that Ken should just DIE! And Ken raises the .22 again, and Dave puts a couple more rounds in to him.
Now, Dave has been shot twice, once directly in the forehead and once in the shoulder. Dave does not know he's been shot, he thinks Ken hit him with the pistol and then shot AT him. He feels pain in his arm and realizes he's been shot there, but it's a grazing wound of no consequence. Ken dies on the floor in a pool of his own blood, having shot first what should have been a fatal shot.
Oh, by the way, as Dave was a known criminal, the local prosecutor charged Dave with 2nd Degree murder based on the notion that he went too far in coming back after escaping down the hallway and shooting Ken again (this is prior to the current Missouri incarnation of the enhanced castle doctrine). A jury took exactly 20 minutes to come back with a 'Not Guilty' verdict based on self-defense.
*All names have been changed to protect those involved. The case is several years old and already adjudicated. The above story comes from witness statements and the statements of 'Dave'......'Ken' could not be reached for comment.