Yes, a street fight is no place for playing around with fancy tactics; it is not sparring. I would not want to slug it out with a street fighter as my first choice of strategy. That's why I'd prefer to control the distance/angles to evade the ferocity of his initial attack and let the attacker create my opening then strongly counter with multiple strikes until the opponent is finished.
If one is of a mind to initiate the attack the same simplicity is required; one's attack must be as direct as possible. When I mentioned guard and set-up, it has to conform to this rule. A "quick" (the term I used in my post) initial feint and then explosively move in, blasting/stuffing his guard to overwhelm the opponent with multiple strikes.
Most untrained fighters don't put much attention to their stance, leaving their leg vulnerable to an initial set-up attack.
Simplicity, directness and aggressive fierce commitment I would list as the key factors no matter which approach is used. This does sound like the street fighter's strategy as well - one must fight fire with fire. The MA guy gets the edge with efficient trained technique and eye. An experienced street fight with some technical training? Oh boy!