I have used pressure points successfully hundreds (thousands?) of times. They're not magic, but they absolutely can be used effectively.are there parts of the body that are more tender or sensitive than others for various reasons? sure. are you going to aggressively poke or jab a finger or two into them and cause enough damage or pain to reliably get away from an attacker or end a fight? hell no.
anyone claiming to teach self defense that teaches pressure points has never been in a real fight before.
One example. Combative patients often try to bite and/or spit. It's very easy to control their head by applying pressure behind the angle of the jaw. You can turn their head to the side and hold it down, which removes most of the typical targets. Pain compliance is a real thing.
There's nothing magic about pressure points, but they're certainly useful in the right situation. And that's all that can be said about any technique you can think of.