OK, not trying to go against Mod warnings but that one actually has me scratching my head.......
The definition of fact is a thing that is indisputably the case.
So facts are used to prove...well...truths and reality.... since "indisputable" means unable to be challenged or denied.....the question is what is actually a fact and what is not....
or it simply could be a case of I missed the joke...if so my apologies.
I believe he was intending that to be somewhat a joke, but also somewhat real.
The reality comes in that, just because a few people here and there have done something, does not necessarily make it likely or probable. Put in the context of this thread. Yes, there have been people with various disabilities who have successfully defended themselves without the use of weapons. However, that does not mean that it is commonplace OR that such persons are not at a disadvantage against persons who do not have to deal with their same conditions. If everything else was equal, the person who does not suffer from the same conditions is at a significant disadvantage, and it is dishonest, and perhaps even dangerous in the context of personal protection, to argue otherwise.
A real-world self-defense situation is typically one where someone else has chosen the time, circumstances, etc. of the engagement. They are working to stack the deck against you as much as you can. As such, the smart play is to do everything one can to put the odds in YOUR favor, not rely on being one of the outliers.
A weapon is the great equalizer for persons who differing bodily abilities. That could mean our OP, a little old lady who is frail, or a younger person coming off of a surgery. There are any number of scenarios.
I'll stick with my original recommendations to the OP. Something that could be fun and functional, such as FMA (mostly due to the weapons consideration) or GJJ, when combined with legit firearms training, would likely be the best combination of choices to satisfy both the fitness and self-defense aspect of things. In addition, I'll stick with my recommendation for exploring some legit strength training. The reality is that, with a few notable exceptions, most of the martial arts training that people are involved doesn't do much at all for fitness, as can easily be noted by the number of overweight and out of shape black belts that exist.