and you named the thread "Kinetic Energy"?
I'm not quite sure what you're getting at (maybe I'm not best placed to answer) but there will be a lot of trade-offs between a much larger fighter against a smaller, more skilled and fitter fighter. I personally don't fancy eating kicks and punches from a 6'5 beginner but being a few years more experienced I'd be confident of being able to get inside without taking too much damage and work from there. There will be similar tradeoffs between an unfit guy with some fundamentals against a fitter opponent who is a complete beginner - although my money would be on the person with a bit of training under thier belt.
It all depends on what we're talking about though. Real street fighting, kickboxing continuous rules, MMA rules....
I might be missing the point youre trying to make entirely!
Edit: I think I understand what you're getting at now - with everything else being equal does having more balance to your body build makeup for being disadvantaged at being the smaller fighter.... If thats what you're getting at then I'm not sure, you'd need to consider a lot of different factors (some of which I've touched upon).