I'm not sure if they covered this one specifically, but Mythbusters did a show not long ago looking at gasoline additives purported to increase gas mileage. On testing, none of the additives made a measurable difference.
As a chemist, there's no way that a couple teaspoons of acetone in your tank is likely to have any effect on gas mileage whatsoever.
One interesting thing from the show was that they also ran a car on used cooking oil (which would otherwise be thrown away). Simply filtered it on the way into the gas tank... and the car ran beautifully. Free fuel is as close as your nearest KFC on "cleaning" day
Might not meet California emission standards, though...
There is a show on this, not sure the channel, but it is two guys who took their car that burns used cooking oil across the USA. (* NOTE: Lots of modifications to the engine and rebuilds and work on it to make it work, in a reliable manner to take it across the country. *) The Channel was History, TLC, or ... not really sure but, if I see it again I will get the info for it.