I've had mild relief with glucosamine. The recommended dose for someone <200 lbs, is to 1,500mg daily (in divided doses) and 2,000mg daily for someone >200lbs. Chondriton is supposed to help absorption of the Glucosamine for max benefit, but I can't say I had better results that way.
Warnings for the above; Chondriton interacts poorly with anti-coagulants (aspirin, coumadin, NSAIDS like motrin, ibuprofen & advil). Glucosamine may inhibit insulin production, so it's not recommended for anyone who is diabetic.
This info comes from a nursing drug manual of alternative medicines I own.
Last thing- ask your pharmacist what companies are most reputable in supplement production. Supplements aren't cheap in the long run, but you don't want to buy crap. Also, you need to take this daily for an effect- it's not like tylenol you take when it hurts.
Hope this helps!