The PA (physician's assistant) said the same thing - that the side effects could range from euphoria and hyperactivity to severe depression (and that's just her and her brother-in-law) or anything in between, and if anything happened that I didn't like, to stop taking it immediately.
Yes, that dovetails with what I've seen and heard amongst people who had it prescribed for them... it's sort of a crapshoot; I hope you're one of the people it works likes magic for.
I may wait on the Prednisone til morning, as things that affect sleep in anyone tend to have that effect on me, but I already took the Mucinex - I didn't realize that guafin (sp?) was being sold over the counter like that, but it worked really well the last time it was prescribed, so I have high hopes for it.
I tend to be medication-resistant. But if you're one of the people who are affected by drowsiness-inducing medication, yes, probably morning is best to take it.
The stuff for loosening up congestion in the lung and broncheal passage, in Mucinex, Robitussin and other meds (I don't know the spelling either!) is much less likely to trigger anything adverse. I hate taking it because, while it's effective, it's also... yucky, is the only word that comes to mind!