Rome thrived for 1,000 years, yet less than 82 years after Christianity was recognized did it split effectively ending the empire. One can argue that it was Christianity that led to the fall of the Roman Empire.
313: Constantine ends the persecution of the Christians (edict of Milano)
313: Constantine recognizes the Christian church.
380: Theodosius I proclaims Christianity as the sole religion of the Roman Empire
395: Theodosius divides the Roman empire in the Western and Eastern Empires, with Milano and Constantinople as their capitals
410: the Visigots sack Roma
Timeline: http://www.scaruffi.com/politics/romans.html
Toss this one around a bit if y'all like.
313: Constantine ends the persecution of the Christians (edict of Milano)
313: Constantine recognizes the Christian church.
380: Theodosius I proclaims Christianity as the sole religion of the Roman Empire
395: Theodosius divides the Roman empire in the Western and Eastern Empires, with Milano and Constantinople as their capitals
410: the Visigots sack Roma
Timeline: http://www.scaruffi.com/politics/romans.html
Toss this one around a bit if y'all like.